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Isatis tinctoria Linn.


Botanical Name	:	Isatis tinctoria Linn.
English Name	:	Dyer's Woad
Synonym(s)	:	Isatis indigotica (Fortune.)
Family	:	Brassicaceae

General Info

Description

A herbaceous biennial, 1½ -3 ft. high, with entire or coarsely toothed radical leaves and small yellow flowers borne on panicled racemes.

Herb Effects

Antiviral, cyanogenetic; antibacterial, antiviral, anticancer and antiparasitic (root)

Links

Isatis tinctoria
Plants for a Future
Monograph

Chemistry

Active Ingredients

Indican, tryptanthrin, hydroxycinnamic acid, ferulic acid, sinapic acid and candidine (leaves); Indirubin, sinigrin (root); kaempferol, quercetin (plant); linoleic acid, oleic acid (seed)

Chemistry of Active Ingredients

Name

CAS#

IUPAC Name

Formula

Structure

Indican

487-60-5

2-(hydroxymethyl)-6-
(1H-indol-3-yloxy)ox
ane-3,4,5-triol

C₁₄H₁₇NO₆

Tryptanthrin

13220-57-0

Not Available

C₁₅H₈N₂O₂

Hydroxycinnamic acid

25429-38-3

(Z)-3-(3-hydroxyphen
yl)prop-2-enoic acid

C₉H₈O₃

Ferulic acid

24276-84-4

3-(4-hydroxy-3-metho
xy-phenyl)prop-2-eno
ic acid

C₁₀H₁₀O₄

Sinapic acid

530-59-6

3-(4-hydroxy-3,5-dim
ethoxy-phenyl)prop-2
-enoic acid

C₁₁H₁₂O₅

Candidine

1405-90-9

(19E,21E,23E,25E,27E
,29E,31E)-33-(4-amin
o-3,5-dihydroxy-6-me
thyl-oxan- 2-yl)oxy
-1,3,4,9,11,17,37-he
ptahydroxy-15,16,18-
trimethyl-7,13-dioxo
-1 4,39-dioxabicycl
o[33.3.1]nonatriacon
ta-19,21,23,25,27,29
,31-heptaene-3 6-ca
rboxylic acid

C₄₇H₇₁NO₁₇

Indirubin

479-41-4

(3E)-3-(3-oxo-1H-ind
ol-2-ylidene)-1H-ind
ol-2-one

C₁₆H₁₀N₂O₂

Sinigrin

534-69-0

3,4,5-trihydroxy-2-(
hydroxymethyl)-6-(1-
sulfooxyiminobut-3-e
nylsulfany l)oxane

C₁₀H₁₇NO₉S₂

Kaempferol

80714-53-0

3-[3-[4,5-dihydroxy-
6-(hydroxymethyl)-3-
[3,4,5-trihydroxy-6-
(hydroxyme thyl)oxa
n-2-yl]oxy-oxan-2-yl
]oxy-4,5-dihydroxy-6
-(hydroxymethyl)oxan
-2 -yl]oxy-4,5-dihy
droxy-2-(4-hydroxyph
enyl)-chromen-7-one

C₃₃H₄₀O₂₁

Quercetin

Not Available

2-(3,4-dihydroxyphen
yl)-3,4,5-trihydroxy
-chromen-7-one

C₁₅H₁₀O₇

Linoleic acid

8024-22-4

Octadeca-9,12-dienoi
c acid

C₁₈H₃₂O₂

Oleic acid

8046-01-3

Octadec-9-enoic acid

C₁₈H₃₄O₂

Pharmacology

Medicinal Use

In meningitis, encephalitis, mumps, influenza, erysipelas, heat rash, gastroenteritis, in high fevers and convulsions in children, coughing of blood and as a detoxifier in infections such as mumps (leaves); in the treatment of fevers, pyogenic inflammation in influenza and meningitis, macula in acute infectious diseases, erysipelas, mumps and epidemic parotitis (roots).Both the leaves and the roots are used in the treatment of pneumonia.

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