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Humulus lupulus Linn.

Botanical Name

Humulus lupulus Linn.

English Name

Hop or Hops

Family

Cannabaceae

General Info

Description

A perennial, twining, scabrid herb, 15-20 ft. in height. Aerial stems (bines) oppositely branched, angular, flexible; leaves opposite, stipulate: lower larger, 3-5 lobed, upper smaller, ovate or cordate, serrate, minutely prickly, petioles long; male flowers small, greenish yellow, arranged in paniculate cymes; female flowers in cone-like inflorescences; fruit an achene.

Herb Effects

Slows down aging of the skin, hypnotic, sedative, decreases libido of males and stimulates the secretion of gastric juices. Aromatic and bitter with sedative, soporific, tonic, anodyne, diuretic, anaphrodisiac, antiseptic, hypnotic, nervine, stomachic and vermifuge

Links

Humulus lupulus L.
Wikipedia, the free encyclopedia
Plants for a Future
King's American Dispensatory

Chemistry

Active Ingredients

Alpha-pinene, arginine, ascorbic acid, astragalin, beta-carotene, beta-eudesmol, beta-pinene, catechin, chlorogenic acid, choline, citral, epicatechin, farnesol, ferulic acid, gamma-aminobutyric acid, gentisic acid, geraniol, isoquercitrin, limonene, lupulin, myrcene, nerol, nerolidol, niacin, p-coumaric acid, p-cymene, phenylalanine, procyanidins, quercitrin, riboflavin, rutin, thiamin, threonine, tryptophan tyrosine (fruit); beta-sitosterol, caffeic acid, delphinidin, myricetin, quercetin (plant); alpha-terpineol, eugenol (essential oil); cannabidiol, kaempferol, (leaf); friedelin, maslinic aicd, oleanolic acid, stigmasterol, ursolic acid (stem); gamma-linolenic acid (seed); humulone, lupulone (flower)

Chemistry of Active Ingredients

Name

CAS#

IUPAC Name

Formula

Structure

Humulone

23510-81-8

(6R)-3,5,6-trihydrox
y-2-(3-methylbutanoy
l)-4,6-bis(3-methylb
ut-2-enyl) cyclohex
a-2,4-dien-1-one

C₂₁H₃₀O₅

Methylbutenol

115-18-4

2-methylbut-3-en-2-o
l

C₅H₁₀O

alpha-Pinene

80-56-8

2,7,7-trimethylbicyc
lo[3.1.1]hept-2-ene

C₁₀H₁₆

Arginine

7004-12-8

2-amino-5-guanidino-
pentanoic acid

C₆H₁₄N₄O₂

Ascorbic acid

Not Available

2-(1,2-dihydroxyethy
l)-4,5-dihydroxy-fur
an-3-one

C₆H₈O₆

Astragalin

480-10-4

4,5-dihydroxy-2-(4-h
ydroxyphenyl)-3-[3,4
,5-trihydroxy-6-(hyd
roxymethyl )oxan-2-
yl]oxy-chromen-7-one

C₂₁H₂₀O₁₁

Beta Carotene

7235-40-7

3,7,12,16-tetramethy
l-1,18-bis(2,6,6-tri
methyl-1-cyclohexeny
l)-octadec a-1,3,5,
7,9,11,13,15,17-nona
ene

C₄₀H₅₆

beta-Eudesmol

473-15-4

2-(4a-methyl-8-methy
lidene-decalin-2-yl)
propan-2-ol

C₁₅H₂₆O

Beta-pinene

23089-32-9

6,6-dimethyl-2-methy
lidene-norpinane

C₁₀H₁₆

Catechin

5323-80-8

2-(3,4-dihydroxyphen
yl)chroman-3,5,7-tri
ol

C₁₅H₁₄O₆

Chlorogenic acid

327-97-9

3-[3-(3,4-dihydroxyp
henyl)prop-2-enoylox
y]-1,4,5-trihydroxy-
cyclohexan e-1-carb
oxylic acid

C₁₆H₁₈O₉

Choline

67-48-1

2-hydroxyethyl-trime
thyl-ammonium

C₅H₁₄NO+

Citral

96680-15-8

3,7-dimethylocta-2,6
-dienal

C₁₀H₁₆O

Epicatechin

490-46-0

2-(3,4-dihydroxyphen
yl)chroman-3,5,7-tri
ol

C₁₅H₁₄O₆

Farnesol

Not Available

3,7,11-trimethyldode
ca-2,6,10-trien-1-ol

C₁₅H₂₆O

Ferulic acid

24276-84-4

3-(4-hydroxy-3-metho
xy-phenyl)prop-2-eno
ic acid

C₁₀H₁₀O₄

gamma-Aminobutyric acid

70582-09-1

4-aminobutanoic acid

C₄H₉NO₂

Gentisic acid

4955-90-2

2,5-dihydroxybenzoic
acid

C₇H₆O₄

Geraniol

8007-13-4

3,7-dimethylocta-2,6
-dien-1-ol

C₁₀H₁₈O

Isoquercitrin

21637-25-2

3-[5-(1,2-dihydroxye
thyl)-3,4-dihydroxy-
oxolan-2-yl]oxy-2-(3
,4-dihydro xyphenyl
)-4,5-dihydroxy-chro
men-7-one

C₂₁H₂₀O₁₂

Limonene

9003-73-0

1-methyl-4-prop-1-en
-2-yl-cyclohexene

C₁₀H₁₆

Myrcene

2153-31-3

7-methyl-3-methylide
ne-octa-1,6-diene

C₁₀H₁₆

Nerol

106-24-1

3,7-dimethylocta-2,6
-dien-1-ol

C₁₀H₁₈O

Nerolidol

14528-94-0

3,7,11-trimethyldode
ca-1,6,10-trien-3-ol

C₁₅H₂₆O

Niacin

99148-57-9

pyridine-3-carboxyli
c acid

C₆H₅NO₂

p-Coumaric acid

501-98-4

3-(4-hydroxyphenyl)p
rop-2-enoic acid

C₉H₈O₃

p-Cymene

Not Available

Dichlororuthenium;
1-methyl-5,6-dihydro
-4H-pyrimidine;
p-cymene

C₁₅H₂₄C_l2N₂Ru

Phenylalanine

3617-44-5

2-amino-3-phenyl-pro
panoic acid

C₉H₁₁NO₂

Procyanidin

4852-22-6

2-(3,4-dihydroxyphen
yl)-2-[2-(3,4-dihydr
oxyphenyl)-5,7-dihyd
roxy-chrom an-3-yl]
oxy-chroman-3,4,5,7-
tetrol

C₃₀H₂₆O₁₃

Quercitrin

6151-25-3

2-(3,4-dihydroxyphen
yl)-4,5-dihydroxy-3-
(3,4,5-trihydroxy-6-
methyl-oxa n-2-yl)o
xy-chromen-7-one

C₂₁H₂₀O₁₁

Riboflavin

Not Available

C₁₇H₂₁N₄O₉P

Rutin

Not Available

2-(3,4-dihydroxyphen
yl)-4,5-dihydroxy-3-
[3,4,5-trihydroxy-6-
[(3,4,5-tr ihydroxy
-6-methyl-tetrahydro
pyran-2-yl)oxymethyl
]tetrahydropyran-2-y
l] oxy-chromen-7-on
e trihydrate

C₂₇H₃₆O₁₉

Thiamin

59-43-8

2-[3-[(4-amino-2-met
hyl-pyrimidin-5-yl)m
ethyl]-4-methyl-1-th
ia-3-azoni acyclope
nta-2,4-dien-5-yl]et
hanol

C₁₂H₁₇N₄OS+

Threonine

632-20-2

2-amino-3-hydroxy-bu
tanoic acid

C₄H₉NO₃

Tryptophan

80206-30-0

2-amino-3-(1H-indol-
3-yl)propanoic acid

C₁₁H₁₂N₂O₂

Tyrosine

556-02-5

2-amino-3-(4-hydroxy
phenyl)-propanoic
acid

C₉H₁₁NO₃

Beta-sitosterol

5779-62-4

17-(5-ethyl-6-methyl
-heptan-2-yl)-10,13-
dimethyl-2,3,4,7,8,9
,11,12,14, 15,16,17
-dodecahydro-1H-cycl
openta[a]phenanthren
-3-ol

C₂₉H₅₀O

Caffeic acid

Not Available

3-(3,4-dihydroxyphen
yl)prop-2-enoic acid

C₉H₈O₄

Delphinidin

528-53-0

[3,7-dihydroxy-2-(3,
4,5-trihydroxyphenyl
)-chromen-5-ylidene]
oxonium ch loride

C₁₅H₁₁ClO₇

Myricetin

529-44-2

3,4,5-trihydroxy-2-(
3,4,5-trihydroxyphen
yl)-chromen-7-one

C₁₅H₁₀O₈

Quercetin

Not Available

2-(3,4-dihydroxyphen
yl)-3,4,5-trihydroxy
-chromen-7-one

C₁₅H₁₀O₇

alpha-Terpineol

10482-56-1

2-(4-methyl-1-cycloh
ex-3-enyl)propan-2-o
l

C₁₀H₁₈O

Eugenol

97-53-0

2-methoxy-4-prop-2-e
nyl-phenol

C₁₀H₁₂O₂

Cannabidiol

13956-29-1

2-[3-methyl-6-(1-met
hylethenyl)-1-cycloh
ex-3-enyl]-5-pentyl-
benzene-1, 3-diol

C₂₁H₃₀O₂

Kaempferol

80714-53-0

3-[3-[4,5-dihydroxy-
6-(hydroxymethyl)-3-
[3,4,5-trihydroxy-6-
(hydroxyme thyl)oxa
n-2-yl]oxy-oxan-2-yl
]oxy-4,5-dihydroxy-6
-(hydroxymethyl)oxan
-2 -yl]oxy-4,5-dihy
droxy-2-(4-hydroxyph
enyl)-chromen-7-one

C₃₃H₄₀O₂₁

Friedelin

559-74-0

4,4a,6a,6b,8a,11,11,
14a-octamethyl-2,4,5
,6,6a,7,8,9,10,12,12
a,13,14,14 b-tetrad
ecahydro-1H-picen-3-
one

C₃₀H₅₀O

Maslinic acid

4373-41-5

10,11-dihydroxy-2,2,
6a,6b,9,9,12a-heptam
ethyl-1,3,4,5,6,6a,7
,8,8a,10,1 1,12,13,
14b-tetradecahydropi
cene-4a-carboxylic
acid

C₃₀H₄₈O₄

Oleanolic acid

508-02-1

10-hydroxy-2,2,6a,6b
,9,9,12a-heptamethyl
-1,3,4,5,6,6a,7,8,8a
,10,11,12,
13,14b-tetradecahydr
opicene-4a-carboxyli
c acid

C₃₀H₄₈O₃

Stigmasterol

4736-55-4

17-(4-ethyl-1,5-dime
thyl-hex-2-enyl)-10,
13-dimethyl-1,2,4,5,
6,7,8,9,10 ,11,12,1
3,14,15,16,17-hexade
cahydrocyclopenta[a]
phenanthren-3-one

C₂₉H₄₈O

Ursolic acid

77-52-1

10-hydroxy-1,2,6a,6b
,9,9,12a-heptamethyl
-2,3,4,5,6,6a,7,8,8a
,10,11,12, 13,14b-t
etradecahydro-1H-pic
ene-4a-carboxylic
acid

C₃₀H₄₈O₃

gamma-Linolenic acid

1686-12-0

(6E,9E,12E)-octadeca
-6,9,12-trienoic
acid

C₁₈H₃₀O₂

Humulone

23510-81-8

(6R)-3,5,6-trihydrox
y-2-(3-methylbutanoy
l)-4,6-bis(3-methylb
ut-2-enyl) cyclohex
a-2,4-dien-1-one

C₂₁H₃₀O₅

Lupulone

Not Available

3,5-dihydroxy-2-(3-m
ethylbutanoyl)-4,6,6
-tris(3-methylbut-2-
enyl)cyclo hexa-2,4
-dien-1-one

C₂₆H₃₈O₄

Pharmacology

Medicinal Use

As a sedative, in digestive maladies, in debility, indigestion, worms, nervous conditions and hair brittleness; to remedy swellings and hardness of the uterus (flower decoction); for boils, bruises, calculus, cancer, cramps, cough, cystitis, debility, delirium, diarrhea, dyspepsia, fever, fits, hysteria, inflammation, insomnia, jaundice, nerves, neuralgia, rheumatism, and worms ; for insomnia, stress and anxiety (dry female buds)

Contraindication

Should not be taken by people suffering with depression. Skin contact with the plant causes dermatitis in sensitive people.

Reference

Stary, Medicinal Herbs and Plants.

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