Citrullus colocynthis (Linn.) Schrad. |
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Botanical Name |
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Citrullus colocynthis (Linn.) Schrad. |
English
Name |
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Bitter Apple. Bitter Cucumber and Colocynth |
Synonym(s) |
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Colocynthis vulgaris Schrad. Cucumis colocynthis. Linn. |
Family |
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Cucurbitaceae |
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General Info
Description |
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A scabrid perennial with prostrate or climbing angular stems and bifid tendrils. Leaves ovate or triangular, deeply 3-lobed, lobes sinuately pinnatifid; flowers monoecious, yellow, solitary, axillary; pepo or gourd 4-10 cm in diam, smooth, globose, green mottled with yellow blotches, pulp bitter, spongy; seeds numerous, white or light brown. |
Herb Effects |
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Hypoglycemic (plant) and laxative (fruit). |
Chemistry
Active Ingredients |
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Ascorbic acid, beta-sitosterol, caffeic acid, chlorogenic acid, citrulline, colocynthin, cucurbitacin-B, ferulic acid, quercitrin (fruit); citrullene, citrulluic acid and scitrullin (fruit juice); alpha-amyrin, linoleic acid, oleic acid, palmitic acid, stearic acid (seed); anethole, anisaldehyde, benzyl-alcohol, citral, lauric acid, limonene, p-cymene (petiole); citronellal, citronellol, methyl-eugenol, oleanolic acid (plant) |
Chemistry
of Active Ingredients |
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Name |
CAS# |
IUPAC Name |
Formula |
Structure |
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Colocynthin |
1398-78-3 |
[6-hydroxy-6-[16-hyd roxy-4,4,9,13,14-pen tamethyl-3,11-dioxo- 2-[3,4,5-t
rihydrox y-6-(hydroxymethyl)o xan-2-yl]oxy-8,10,12 ,15,16,17-hexahydro- 7H
-cyclopenta[a]ph enanthren-17-yl]-2-m ethyl-5-oxo-hept-3-e n-2-yl] acetat
e |
C38H54O13 |
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Ascorbic acid |
Not Available |
2-(1,2-dihydroxyethy l)-4,5-dihydroxy-fur an-3-one |
C6H8O6 |
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beta-Sitosterol |
5779-62-4 |
17-(5-ethyl-6-methyl -heptan-2-yl)-10,13- dimethyl-2,3,4,7,8,9 ,11,12,14,
15,16,17 -dodecahydro-1H-cycl openta[a]phenanthren -3-ol |
C29H50O |
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Caffeic acid |
Not Available |
3-(3,4-dihydroxyphen yl)prop-2-enoic acid |
C9H8O4 |
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Chlorogenic acid |
327-97-9 |
3-[3-(3,4-dihydroxyp henyl)prop-2-enoylox y]-1,4,5-trihydroxy- cyclohexan
e-1-carb oxylic acid |
C16H18O9 |
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Citrulline |
627-77-0 |
2-amino-5-carbamoyla mino-pentanoic acid |
C6H13N3O3 |
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Cucurbitacin B |
Not Available |
[6-(2,16-dihydroxy-4 ,4,9,13,14-pentameth yl-3,11-dioxo-2,7,8, 10,12,15,1
6,17-oct ahydro-1H-cyclopenta [a]phenanthren-17-yl )-6-hydroxy-2-methyl -5
-oxo-hept-3-en-2 -yl] acetate |
C32H46O8 |
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Ferulic acid |
24276-84-4 |
3-(4-hydroxy-3-metho xy-phenyl)prop-2-eno ic acid |
C10H10O4 |
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Quercitrin |
6151-25-3 |
2-(3,4-dihydroxyphen yl)-4,5-dihydroxy-3- (3,4,5-trihydroxy-6- methyl-oxa
n-2-yl)o xy-chromen-7-one |
C21H20O11 |
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alpha-Amyrin |
638-95-9 |
4,4,6a,6b,8a,11,12,1 4b-octamethyl-2,3,4a ,5,6,7,8,9,10,11,12, 12a,14,14a
-tetrade cahydro-1H-picen-3-o l |
C30H50O |
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Linoleic acid |
8024-22-4 |
Octadeca-9,12-dienoi c acid |
C18H32O2 |
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Oleic acid |
8046-01-3 |
octadec-9-enoic acid |
C18H34O2 |
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Palmitic acid |
66321-94-6 |
hexadecanoic acid |
C16H32O2 |
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Stearic acid |
82497-27-6 |
octadecanoic acid |
C18H36O2 |
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Anethole |
8022-08-0 |
1-methoxy-4-prop-1-e nyl-benzene |
C10H12O |
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Anisaldehyde |
50984-52-6 |
4-methoxybenzaldehyd e |
C8H8O2 |
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Benzyl alcohol |
185532-71-2 |
phenylmethanol |
C7H8O |
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Citral |
96680-15-8 |
3,7-dimethylocta-2,6 -dienal |
C10H16O |
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Lauric acid |
8045-27-0 |
Dodecanoic acid |
C12H24O2 |
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Limonene |
9003-73-0 |
1-methyl-4-prop-1-en -2-yl-cyclohexene |
C10H16 |
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p-Cymene |
Not Available |
Dichlororuthenium; 1-methyl-5,6-dihydro -4H-pyrimidine; p-cymene |
C15H24Cl2N2Ru |
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Citronellal |
26489-02-1 |
3,7-dimethyloct-6-en al |
C10H18O |
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Citronellol |
26489-01-0 |
3,7-dimethyloct-6-en -1-ol |
C10H20O |
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Oleanolic acid |
508-02-1 |
10-hydroxy-2,2,6a,6b ,9,9,12a-heptamethyl -1,3,4,5,6,6a,7,8,8a ,10,11,12,
13,14b-t etradecahydropicene- 4a-carboxylic acid |
C30H48O3 |
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Pharmacology
Medicinal Use |
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Rheumatism, urinary disorders and jaundice (root); for constipation, amenorrhea and dropsy (Colocynth pulp which is freed from seeds); Diabetes (plant). |
Reference |
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Chandel et al., Biodiversity in Medicinal and Aromatic Plants in India.
Bentley and Trimen, Medicinal Plants.
Johnson T. CRC Ethnobotany Desk Reference (www.herbweb.com/herbage). |
Dealers
Products
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