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Botanical Name |
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Centella asiatica |
English
Name |
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Indian or Water Pennywort, Marsh Penny, Gotu-Kola and Sneezewort |
Synonym(s) |
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Hydrocotyle asiatica Linn, Hydrocotyle nummularioidesRich, Hydrocotyle pallida DC.&c. |
Family |
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Apiaceae |
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General Info
Description |
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It is a prostrate, perennial herb. The stem is glabrous, pink and striated, rooting at the nodes. The leaves are fleshy, orbicular-reniform, crenate, base cordate and often lobed and long-petioled. The flowers are red, pink or white, in fascicled umbels. The fruits are oblong, dull brown, laterally compressed; the pericarp hard, thickened, woody and white. |
Herb Effects |
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Antiprotozoal, alleviates spasms and sedative (plant); on keratinization and collagen synthesis (stimulates hair and nail growth and provides support for the repair of cartilagen); neutralizes acids in the blood, antiinflammatory, laxative (mild), diuretic, antispasmodic. |
Chemistry
Active Ingredients |
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Ascorbic acid, beta-carotene, beta-elemene, niacin, pectin, riboflavin, thiamin(leaf); asiatic acid, asiaticoside, aspartic acid, beta-sitosterol, betulinic acid, brahminoside, brahmoside, glycine, inositol, kaempferol, linoleic acid, oleic acid, palmitic acid, stigmasterol (plant); camphor (essential oil) |
Chemistry
of Active Ingredients |
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Name |
CAS# |
IUPAC Name |
Formula |
Structure |
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Ascorbic acid |
Not Available |
2-(1,2-dihydroxyethy l)-4,5-dihydroxy-fur an-3-one |
C6H8O6 |
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beta-Carotene |
Not Available |
3,7,12,16-tetramethy l-1,18-bis(2,6,6-tri methyl-1-cyclohexeny l)-octadec
a-1,3,5, 7,9,11,13,15,17-nona ene |
C40H56 |
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Beta-elemene |
33880-83-0 |
1-ethenyl-1-methyl-2 ,4-diprop-1-en-2-yl- cyclohexane |
C15H24 |
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Niacin |
99148-57-9 |
pyridine-3-carboxyli c acid |
C6H5NO2 |
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Riboflavin |
Not Available |
Not Available |
C17H21N4O9P |
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Thiamin |
59-43-8 |
2-[3-[(4-amino-2-met hyl-pyrimidin-5-yl)m ethyl]-4-methyl-1-th ia-3-azoni
acyclope nta-2,4-dien-5-yl]et hanol |
C12H17N4OS+ |
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Asiatic acid |
Not Available |
(1S,2R,4aS,6aS,6bR,9 R,10R,11R,12aR,14bR) -10,11-dihydroxy-9-( hydroxymet
hyl)-1,2 ,6a,6b,9,12a-hexamet hyl-2,3,4,5,6,6a,7,8 ,8a,10,11,12,13,14b- te
tradecahydro-1H- picene-4a-carboxylic acid |
C30H48O5 |
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Asiaticoside |
Not Available |
[6-[[3,4-dihydroxy-6 -(hydroxymethyl)-5-( 3,4,5-trihydroxy-6-m ethyl-oxan
-2-yl)ox y-oxan-2-yl]oxymethy l]-3,4,5-trihydroxy- oxan-2-yl] 10,11-dihyd
roxy-9- (hydroxymethyl)-1,2, 6a,6a,9,12a-hexameth yl-1,2,3,4,4a,5,6,6b ,7,
8,8a,10,11,12,1 3,14b-hexadecahydrop icene-4-carboxylate |
C48H78O19 |
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Aspartic acid |
6899-03-2 |
2-aminobutanedioic acid |
C4H7NO4 |
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Beta-sitosterol |
5779-62-4 |
17-(5-ethyl-6-methyl -heptan-2-yl)-10,13- dimethyl-2,3,4,7,8,9 ,11,12,14,
15,16,17 -dodecahydro-1H-cycl openta[a]phenanthren -3-ol |
C29H50O |
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Betulinic Acid |
4481-62-3 |
Not Available |
C30H46O3 |
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Glycine |
87867-94-5 |
2-aminoacetic acid |
C2H5NO2 |
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Inositol |
551-72-4 |
cyclohexane-1,2,3,4, 5,6-hexol |
C6H12O6 |
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Kaempferol |
80714-53-0 |
3-[3-[4,5-dihydroxy- 6-(hydroxymethyl)-3- [3,4,5-trihydroxy-6- (hydroxyme
thyl)oxa n-2-yl]oxy-oxan-2-yl ]oxy-4,5-dihydroxy-6 -(hydroxymethyl)oxan -2
-yl]oxy-4,5-dihy droxy-2-(4-hydroxyph enyl)-chromen-7-one |
C33H40O21 |
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Linoleic acid |
8024-22-4 |
Octadeca-9,12-dienoi c acid |
C18H32O2 |
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Oleic acid |
8046-01-3 |
Octadec-9-enoic acid |
C18H34O2 |
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Palmitic acid |
66321-94-6 |
hexadecanoic acid |
C16H32O2 |
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Stigmasterol |
4736-55-4 |
17-(4-ethyl-1,5-dime thyl-hex-2-enyl)-10, 13-dimethyl-1,2,4,5, 6,7,8,9,10
,11,12,1 3,14,15,16,17-hexade cahydrocyclopenta[a] phenanthren-3-one |
C29H48O |
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Camphor |
8022-77-3 |
1,7,7-trimethylnorbo rnan-2-one |
C10H16O |
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Pharmacology
Medicinal Use |
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For healing wounds (plant extract); in tuberculosis and leprosy (plant decoction); improves intellectual capacity, concentration and memory of children, in skin diseases, asthma, bronchitis, gastric problems, leucorrhea, catarrh, as an antidote in cholera; on boils and tumours (plant paste); to cure severe headache, to prevent and cure urinary tract infections and the growth of kidney stones (leaf juice). |
Contraindication |
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The raw leaf juice should be consumed in small doses. since it is very potent and an excess may lead to coma. Nausea has been reported at very high levels of intake. It should not be taken internally as a supplement by children under 4 or breast-feeding / pregnant mothers. People taking sedatives should also not use centella as a supplement. |
Reference |
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Chandel et al., Biodiversity in Medicinal and Aromatic Plants in India.
Johnson T. CRC Ethnobotany Desk Reference (www.herbweb.com/herbage).
Uniyal et al., Medicinal Flora of Garhwal Himalayas. |
Dealers
Products
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