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Botanical Name |
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Calotropis procera R.BR. |
English
Name |
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Swallow Wart, Milkweed, Dead Sea Apple and Sodom Apple |
Synonym(s) |
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Calotropis hamiltonii Wight., Asclepias procera Willd. |
Family |
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Asclepiadaceae |
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General Info
Description |
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Erect, tall, large, much branched and perennial shrubs or small trees that grow to a height of 5.4 m., with milky latex throughout. Bark is soft and corky. Branches stout, terete with fine appressed cottony pubescence (especially on young). Leaves sub-sessile, opposite, decusate, broadly ovate-oblong, elliptic or obovate, acute, thick, glaucous, green, covered with fine cottony pubescent hair on young but glabrous later and base cordate. Flowers in umbellate-cymes and tomentose on young. Calyx glabrous, ovate and acute. Corolla glabrous, lobes errect, ovate, acute, coronal scales 5-6, latterly compressed and equally of exceeding the staminal column. Folicles are sub-globose or ellipsoid or ovoid. Seeds broadly ovate, acute, flattened, minutely tomentose, brown coloured and silky coma is 3.2 cm long. |
Herb Effects |
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Expectorant, stimulant and diaphoretic (root bark); anticancer and stimulates the cardiovascular system and respiration (root and leaf); induces vomiting (in large doses); tonic, appetiser, stomachic (flower). |
Chemistry
Active Ingredients |
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Taraxasterol and its y-isomer, taraxasteryl isovalerate, taraxasteryl acetate, giganteol, gigantin, isogiganteol and a wax (root bark); calotoxin, uscharidin and uscharin (plant and latex); alpha and beta-amyrin and beta-sitosterol (root bark and plant). |
Chemistry
of Active Ingredients |
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Name |
CAS# |
IUPAC Name |
Formula |
Structure |
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Taraxasteryl acetate |
6426-43-3 |
(4,4,6a,6b,8a,12,14b -heptamethyl-11-meth ylidene-1,2,3,4a,5,6 ,6a,7,8,9,
10,12,12 a,13,14,14a-hexadeca hydropicen-3-yl) acetate |
C32H52O2 |
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Calotoxin |
20304-49-8 |
Not Available |
C29H40O10 |
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Uscharidin |
24321-47-9 |
Not Available |
C29H38O9 |
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Beta-sitosterol |
5779-62-4 |
17-(5-ethyl-6-methyl -heptan-2-yl)-10,13- dimethyl-2,3,4,7,8,9 ,11,12,14,
15,16,17 -dodecahydro-1H-cycl openta[a]phenanthren -3-ol |
C29H50O |
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Taraxasterol |
1059-14-9 |
4,4,6a,6b,8a,12,14b- heptamethyl-11-methy lidene-1,2,3,4a,5,6, 6a,7,8,9,1
0,12,12a ,13,14,14a-hexadecah ydropicen-3-ol |
C30H50O |
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Calotoxin |
20304-49-8 |
Not Available |
C29H40O10 |
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alpha-Amyrin |
638-95-9 |
4,4,6a,6b,8a,11,12,1 4b-octamethyl-2,3,4a ,5,6,7,8,9,10,11,12, 12a,14,14a
-tetrade cahydro-1H-picen-3-o l |
C30H50O |
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beta-Amyrin |
559-70-6 |
4,4,6a,6b,8a,11,11,1 4b-octamethyl-1,2,3, 4a,5,6,7,8,9,10,12,1 2a,14,14a-
tetradec ahydropicen-3-ol |
C30H50O |
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Beta-sitosterol |
5779-62-4 |
17-(5-ethyl-6-methyl -heptan-2-yl)-10,13- dimethyl-2,3,4,7,8,9 ,11,12,14,
15,16,17 -dodecahydro-1H-cycl openta[a]phenanthren -3-ol |
C29H50O |
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Pharmacology
Medicinal Use |
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Dysentery, diarrhea, indigestion, reducing fever, leprosy, skin diseases and eczema (root bark); cough, cold and asthma (flower and root bark); toothache (latex); rheumatism and syphilis; to relieve stomach pain (leaves); cures piles, asthma, cholera and wounds (flowers). |
Contraindication |
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Large doses cause vomiting and diarrhoea. |
Reference |
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Chandel et al., Biodiversity in Medicinal and Aromatic Plants in India.
Uniyal et al., Medicinal Flora of Garhwal Himalayas.
Bentley and Trimen, Medicinal Plants.
The Himalaya Drug Company.
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Dealers
Products
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