| |
|
|
Botanical Name |
: |
Caesalpinia sappan L. |
English
Name |
: |
Brazil Wood Tree |
Synonym(s) |
: |
Biancaea sappan (L.)Tod. |
Family |
: |
Caesalpiniaceae |
| |
General Info
| Description |
 |
|
A spreading tree or shrub, up to 10 m in height. Branchlets dull, lenticellate, usually armed with paired, recurved prickles; leaves large hairy to glabrous, pinnae 9-14 pairs, hairy, leaflets 10-20 pairs per pinna, oblong, membranous, obliquely truncate; flowers yellow, in supra-axillary and terminal racemes combining into a large panicle; pods green, 3-4 seeded, beaked; seeds ellipsoid, black. |
| Herb Effects |
|
|
Semen coagulant and anticancer (stem); antiinflammatory (heartwood); astringent and emmenagogue (infusion of wood) |
Chemistry
| Active Ingredients |
|
|
Beta-amyrin glucoside, brazilin, aspartic acid, glycine, alanine, proline, leucine, sappanin, valine and threonine (heartwood). |
| Chemistry
of Active Ingredients |
|
|
|
 |
Name |
CAS# |
IUPAC Name |
Formula |
Structure |
 |
|
| Beta-Amyrin |
559-70-6 |
4,4,6a,6b,8a,11,11,1
4b-octamethyl-1,2,3,
4a,5,6,7,8,9,10,12,1
2a,14,14a-
tetradec
ahydropicen-3-ol |
C30H50O |
|
| Brazilin |
474-07-7 |
Not Available |
C16H14O5 |
|
| Aspartic acid |
6899-03-2 |
2-aminobutanedioic
acid |
C4H7NO4 |
|
| Glycine |
87867-94-5 |
2-aminoacetic acid |
C2H5NO2 |
|
| Alanine |
35597-43-4 |
2-[2-[2-amino-4-(hyd
roxy-methyl-phosphor
yl)-butanoyl]aminopr
opanoylami
no]propa
noic acid |
C11H22N3O6P |
|
| Proline |
344-25-2 |
pyrrolidine-2-carbox
ylic acid |
C5H9NO2 |
|
| Leucine |
2439-37-4 |
2-dimethylamino-4-me
thyl-pentanoic acid |
C8H17NO2 |
|
| Valine |
7004-03-7 |
2-amino-3-methyl-but
anoic acid |
C5H11NO2 |
|
| Threonine |
632-20-2 |
2-amino-3-hydroxy-bu
tanoic acid |
C4H9NO3 |
|
|
Pharmacology
| Medicinal Use |
|
|
Dysentery and diarrhea, and its paste in rheumatism, haemorrhages and to treat wounds (wood decoction) |
| Contraindication |
|
|
Used with caution in pregnancy. |
| Reference |
|
|
 Chandel et al., Biodiversity in Medicinal and Aromatic Plants in India.
Choi SY. Yang KM. Jeon SD. Kim JH. Khil LY. Chang TS. Moon CK. Brazilin modulates immune function mainly by augmenting T cell activity in halothane administered mice. Planta Med. |
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