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Botanical Name |
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Digitalis purpurea Linn. |
English
Name |
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Digitalis, Foxglove, Witches' Gloves, Dead Men's Bells, Fairy's Glove, Gloves of Our Lady. Bloody Fingers. Virgin's Glove. Fairy Caps. Folk's Glove an |
Synonym(s) |
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Digitalis tomentosa and Digitalis folia |
Family |
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Scrophulariaceae |
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General Info
Description |
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Biennial or perennial herb growing as high as roughly 1.2 meters. It bears during the first year, a rosette of radical, rugose, somewhat downy leaves, 6-12 in. long, ovate to ovate-lanceolate with long winged petioles; from the centre of the leaf rosette arises, in the second year, a single, erect, flowering axis with sessile and sub-sessile leaves terminating in a one-sided raceme of flowers, 2-3 in. long,
declined, tubular-campanulate, purple, yellow or white; seeds small, light and numerous. |
Herb Effects |
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Cardiotonic, diuretic, stimulant and tonic (leaf); promotes and stimulates the activity of all muscle tissues, improves blood flow to the kidneys and aids in removing any obstructions there thus improving urination, poisonous (can be fatal in high doses) and sedative. |
Chemistry
Active Ingredients |
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Digitoxin (a highly toxic and cumulative compound) and digitalin (both are insoluble in water); also digitalein which is soluble in water and lanatosides; acetic acid, acetyl-choline, benzoic acid, caffeic acid, chlorogenic acid, choline, citric acid, digitoxin, ferulic acid, formic acid, gallic acid, gitoxin, gitalin, luteolin, p-coumaric acid (leaf); apigenin (flower) |
Chemistry
of Active Ingredients |
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Name |
CAS# |
IUPAC Name |
Formula |
Structure |
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Digitoxin |
82476-56-0 |
4-[3-[5-[5-(4,5-dihy droxy-6-methyl-oxan- 2-yl)oxy-4-hydroxy-6 -methyl-ox
an-2-yl] oxy-4-hydroxy-6-meth yl-oxan-2-yl]oxy-14- hydroxy-10,13-dimeth yl
-1,2,3,4,5,6,7,8 ,9,11,12,15,16,17-te tradecahydrocyclopen ta[a]phenanthr
en-1 7-yl]-5H-furan-2-one |
C41H64O13 |
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Digitalin |
8001-36-3 |
4-[14,16-dihydroxy-3 -[3-hydroxy-4-methox y-6-methyl-5-[3,4,5- trihydroxy
-6-(hydr oxymethyl)oxan-2-yl] oxy-oxan-2-yl]oxy-10 ,13-dimethyl-1,2,3,4 ,5
,6,7,8,9,11,12,1 5,16,17-tetradecahyd rocyclopenta[a]phena nthren-17-yl]-
5H-f uran-2-one |
C36H56O14 |
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Gitoxin |
4562-36-1 |
4-[3-[5-[5-(4,5-dihy droxy-6-methyl-oxan- 2-yl)oxy-4-hydroxy-6 -methyl-ox
an-2-yl] oxy-4-hydroxy-6-meth yl-oxan-2-yl]oxy-14, 16-dihydroxy-10,13-d im
ethyl-1,2,3,4,5, 6,7,8,9,11,12,15,16, 17-tetradecahydrocyc lopenta[a]phen
anth ren-17-yl]-5H-furan- 2-one |
C41H64O14 |
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Acetic acid |
77671-22-8 |
acetic acid |
C2H4O2 |
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Benzoic acid |
8013-63-6 |
benzoic acid |
C7H6O2 |
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Caffeic acid |
Not Available |
3-(3,4-dihydroxyphen yl)prop-2-enoic acid |
C9H8O4 |
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Chlorogenic acid |
327-97-9 |
3-[3-(3,4-dihydroxyp henyl)prop-2-enoylox y]-1,4,5-trihydroxy- cyclohexan
e-1-carb oxylic acid |
C16H18O9 |
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Choline |
67-48-1 |
2-hydroxyethyl-trime thyl-ammonium |
C5H14NO+ |
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Citric acid |
Not Available |
2-hydroxypropane-1,2 ,3-tricarboxylic acid |
C6H8O7 |
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Ferulic acid |
24276-84-4 |
3-(4-hydroxy-3-metho xy-phenyl)prop-2-eno ic acid |
C10H10O4 |
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Formic acid |
992-98-3 |
formic acid |
CH2O2 |
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Gallic acid |
149-91-7 |
3,4,5-trihydroxybenz oic acid |
C7H6O5 |
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Luteolin |
Not Available |
2-(3,4-dihydroxyphen yl)-4,5-dihydroxy-ch romen-7-one |
C15H10O6 |
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p-Coumaric acid |
501-98-4 |
3-(4-hydroxyphenyl)p rop-2-enoic acid |
C9H8O3 |
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Apigenin |
520-36-5 |
4,5-dihydroxy-2-(4-h ydroxyphenyl)-chrome n-7-one |
C15H10O5 |
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Pharmacology
Medicinal Use |
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Should be taken under close scrutiny because of its toxic properties; for mainly heart disease but also palpitations, maladies of the kidney, wounds, burns, asthma, edema, fever, mental disorders, neuralgia and abdominal tumors. Used as myocardial stimulant in congested heart failure, auricular flutter and rapid auricular fibrillation. |
Contraindication |
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All parts of the plants are poisonous. |
Reference |
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Chandel et al., Biodiversity in Medicinal and Aromatic Plants in India.
Bentley and Trimen, Medicinal Plants.
Grieve M. A Modern Herbal (1931) (www.botanical.com).
Johnson T. CRC Ethnobotany Desk Reference (www.herbweb.com/herbage). |
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