Catharanthus roseus (L.) G.DON. |
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Botanical Name |
: |
Catharanthus roseus (L.) G.DON. |
English
Name |
: |
Periwinkle |
Synonym(s) |
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Lochnera rosea (L.) Spach, Vinca rosea L. |
Family |
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Apocynaceae |
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General Info
| Description |
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A small herb or subshrub, up to 75 cm high; leaves elliptic-ovate to oblong, 4 to 10 by 2 to 4 cm, glabrous to puberulous, base acute or cuneate, apex obtusely apiculate, lateral nerves 10 to 12 pairs, petiole 1.0 to 1.5 cm; flowers in axillary or terminal cymes; solitary or paired, shortly pedicellate, pink or white or white with pink or yellow ring in orifice region; mericarps 3 to 4 by 0.3 cm, puberulous. |
| Herb Effects |
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Antitumor and depresses the central nervous system. Bitter, acidic, sedative, as stomachic, tranquilizer and as tonic (root) |
Chemistry
| Active Ingredients |
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Adenosine, tannin, ursolic acid, (leaf); ajmalicine, akuammicine, akuammine, beta-sitosterol, choline, kaempferol, leuroscristine, mitraphylline, oleanolic acid, protocatechuic acid, quercetin, reserpine, serpentine, sweroside, vinblastine, vincamine, vincaleucoblastine, vincoside, vincristine, yohimbine (plant). |
| Chemistry
of Active Ingredients |
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|
 |
Name |
CAS# |
IUPAC Name |
Formula |
Structure |
 |
|
| Vincaleucoblastine |
Not Available |
Not Available |
C46H58N4O13S |
|
| Adenosine |
Not Available |
2-(6-aminopurin-9-yl
)-5-(hydroxymethyl)o
xolane-3,4-diol |
C10H13N5O4 |
|
| Tannin |
1401-55-4 |
Not Available |
C27H22O18 |
|
| Ursolic acid |
77-52-1 |
10-hydroxy-1,2,6a,6b
,9,9,12a-heptamethyl
-2,3,4,5,6,6a,7,8,8a
,10,11,12, |
C30H48O3 |
|
| Ajmalicine |
483-04-5 |
Not Available |
C21H24N2O3 |
|
| Akuammicine |
Not Available |
Not Available |
C20H22N2O2 |
|
| Akuammine |
3512-87-6 |
Not Available |
C22H26N2O4 |
|
| Beta-sitosterol |
5779-62-4 |
17-(5-ethyl-6-methyl
-heptan-2-yl)-10,13-
dimethyl-2,3,4,7,8,9
,11,12,14,
15,16,17
-dodecahydro-1H-cycl
openta[a]phenanthren
-3-ol |
C29H50O |
|
| Choline |
67-48-1 |
2-hydroxyethyl-trime
thyl-ammonium |
C5H14NO+ |
|
| Kaempferol |
80714-53-0 |
3-[3-[4,5-dihydroxy-
6-(hydroxymethyl)-3-
[3,4,5-trihydroxy-6-
(hydroxyme
thyl)oxa
n-2-yl]oxy-oxan-2-yl
]oxy-4,5-dihydroxy-6
-(hydroxymethyl)oxan
-2
-yl]oxy-4,5-dihy
droxy-2-(4-hydroxyph
enyl)-chromen-7-one |
C33H40O21 |
|
| Mitraphylline |
509-80-8 |
Not Available |
C21H24N2O4 |
|
| Oleanolic acid |
508-02-1 |
10-hydroxy-2,2,6a,6b
,9,9,12a-heptamethyl
-1,3,4,5,6,6a,7,8,8a
,10,11,12,
13,14b-t
etradecahydropicene-
4a-carboxylic acid |
C30H48O3 |
|
| Protocatechuic acid |
5417-95-8 |
N,N-diethyl-N'-(2,4,
8,9-tetrazabicyclo[4
.3.0]nona-2,4,7,10-t
etraen-5-y
l)propan
e-1,3-diamine |
C12H20N6 |
|
| Quercetin |
Not Available |
2-(3,4-dihydroxyphen
yl)-3,4,5-trihydroxy
-chromen-7-one |
C15H10O7 |
|
| Reserpine |
Not Available |
Not Available |
C33H40N2O9 |
|
| Serpentine |
58782-36-8 |
Not Available |
C21H21N2O3+ |
|
| Sweroside |
14215-86-2 |
(1S,9S,10S)-10-ethen
yl-9-[(2S,3R,4S,5R,6
R)-3,4,5-trihydroxy-
6-(hydroxy
methyl)o
xan-2-yl]oxy-4,8-dio
xabicyclo[4.4.0]dec-
6-en-5-one |
C16H22O9 |
|
| Vinblastine |
865-21-4 |
Not Available |
C46H58N4O9 |
|
| Vincamine |
1617-90-9 |
Not Available |
C21H26N2O3 |
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| Vincristine |
2068-78-2 |
Not Available |
C46H58N4O14S |
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| Yohimbine |
65-19-0 |
Not Available |
C21H26N2O3 |
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Pharmacology
| Medicinal Use |
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Diabetes and as a wasp sting antidote; for cancer (dried plant); to Hodgkin's disease, menorrhagia and diabetes (dried leaves); mixed with cow dung is used externally for cuts and wounds (pulp of nodes); diabetes, menorrhagia, leukemia and stomach-ache (whole plant); in menorrhagia and the juice for wasp-stings (leaf infusion). |
| Reference |
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 Chandel et al., Biodiversity in Medicinal and Aromatic Plants in India.
Johnson T. CRC Ethnobotany Desk Reference (www.herbweb.com/herbage). |
Dealers
Products
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