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Botanical Name |
: |
Canscora decussata |
English
Name |
: |
Canscora |
Synonym(s) |
: |
Exacum alatum Roth., Pladera decussata Roxb. , Canscora diffusa |
Family |
: |
Gentianaceae |
| |
General Info
| Description |
 |
|
A slender, erect, annual herb up to 60 cm tall. Leaves narrowly ovate to oblong lanceolate, 0.5 to 4.0 cm long and 0.4 to 1.6 cm wide, apex, acute, base subcordate to rounded, basally three nerved. Flowers white borne in lax cymes; calyx 8 to 13 mm long, 4 winged; corolla tube as long as the calyx, lobes 6 mm long, obovate. Fruits capsules linear-oblong, 6 to 8 mm long and 2 mm broad, obutse at apex, persistent style at the tip. |
| Herb Effects |
|
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Antitubercular (flower tops and root) and anticonvulsant (plant); nervine and alterative tonic. |
Chemistry
| Active Ingredients |
|
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Gluanone, sitosterol, canscoridione, loliolide, stigmasterol, campesterol and a combination of n-alkanols and n-alkanes (aerial part); polyoxygenated xanthones (root and flower tops). |
| Chemistry
of Active Ingredients |
|
|
|
 |
Name |
CAS# |
IUPAC Name |
Formula |
Structure |
 |
|
| Sitosterol |
5779-62-4 |
17-(5-ethyl-6-methyl
-heptan-2-yl)-10,13-
dimethyl-2,3,4,7,8,9
,11,12,14,
15,16,17
-dodecahydro-1H-cycl
openta[a]phenanthren
-3-ol |
C29H50O |
|
| Loliolide |
1133-03-5 |
6-hydroxy-4,4,7a-tri
methyl-6,7-dihydro-5
H-benzofuran-2-one |
C11H16O3 |
|
| Stigmasterol |
4736-55-4 |
17-(4-ethyl-1,5-dime
thyl-hex-2-enyl)-10,
13-dimethyl-1,2,4,5,
6,7,8,9,10
,11,12,1
3,14,15,16,17-hexade
cahydrocyclopenta[a]
phenanthren-3-one |
C29H48O |
|
| Campesterol |
474-62-4 |
17-(5,6-dimethylhept
an-2-yl)-10,13-dimet
hyl-2,3,4,7,8,9,11,1
2,14,15,16
,17-dode
cahydro-1H-cyclopent
a[a]phenanthren-3-ol |
C28H48O |
|
|
Pharmacology
| Medicinal Use |
|
|
Nerve disorders, in insanity, scrofula and epilepsy (plant decoction); as laxative and tonic; as a febrifuge; to promote memory power, cure leprosy, ulcers, oedema, urinary disorders and snake-bites; to treat liver disorders, intermittent fever, leucoderma, tuberculosis, inflammation and abdominal troubles. |
| Contraindication |
|
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None known |
| Reference |
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|
 Chandel et al., Biodiversity in Medicinal and Aromatic Plants in India.
Dikshit et al., Indian J Physiol Pharmacol. 1972 16, 81.
Ghosal S, Biswas K, Chaudhuri RK. Chemical constituents of Gentianaceae XXIV: Anti-Mycobacterium tuberculosis activity of naturally occurring xanthones and synthetic analogs. J Phar. |
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