Choline, betaine, various amino acids and plastoquinones (leaf); carotenes, vitamins, acetylcholine, histamine, formic acid and 5-hydroxytryptamine (plant).
Chemistry
of Active Ingredients
Name
CAS#
IUPAC Name
Formula
Structure
Choline
67-48-1
2-hydroxyethyl-trime thyl-ammonium
C5H14NO+
Betaine
590-47-6
Carboxymethyl-trimet hyl-ammonium hydroxide
C5H13NO3
5-Hydroxytryptamine
Not Available
3-(2-aminoethyl)-1H- indol-5-ol
C10H12N2O
Pharmacology
Medicinal Use
Jaundice, kidney problems, bleeding of the uterus and nose, excessive menstruation, haemorrhoids, arthritis, rheumatism and eczema, as a diuretic (for relieving rheumatism and edema), astringent and as a substitute for thiazide treatment (without side effects) (plant); Externally, the plant is used to treat skin complaints, arthritic pain, gout, sciatica, neuralgia, haemorrhoids, dandruff etc.; as a tonic (flower and seed); for heart problems. Nettles have a long history of Use(s) in the home as a herbal remedy and nutritious addition to the diet. A tea made from the leaves has traditionally been used as a cleansing tonic and blood purifier so the plant is often used in the treatment of hay fever, arthritis, anaemia etc.
Contraindication
It may lower blood pressure and heart rate. Leaf extract (IDS 23, Rheuma-Hek) reduces TNF-alpha & IL-1 beta in healthy humans induced by LPS. No effect on IL6 (Obertreis et al., 1996).
Reference
Chandel et al., Biodiversity in Medicinal and Aromatic Plants in India.
Uniyal et al., Medicinal Flora of Garhwal Himalayas. Stary, The Natural Guide to Medicinal Herbs and Plants.