Allamanda cathartica Linn. |
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Botanical Name |
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Allamanda cathartica Linn. |
English
Name |
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Campanilla |
Synonym(s) |
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Allamanda hendersonii Bull ex Dombrain |
Family |
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Apocynaceae |
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General Info
| Description |
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An erect, evergreen, variable shrub, up to 4 m in height. Leaves whorled, obovate to oblong-lanceolate, 8-12 cm ° 2.5-4.0 cm, wavy; flowers large, showy, bright- or golden-yellow, in terminal, cymose panicles; capsules prickly; seeds many, obovate, flat, winged. |
| Herb Effects |
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Antifungal (flower); against human carcinoma cells of the nasopharynx (in vitro) and against leukemia (in vivo) (50% EtOH extract of roots). |
Chemistry
| Active Ingredients |
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Ursolic acid, beta-amyrin and beta-sitosterol (leaf); plumericin and isoplumericin (stem and root bark). |
| Chemistry
of Active Ingredients |
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Name |
CAS# |
IUPAC Name |
Formula |
Structure |
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| Ursolic acid |
77-52-1 |
10-hydroxy-1,2,6a,6b
,9,9,12a-heptamethyl
-2,3,4,5,6,6a,7,8,8a
,10,11,12, |
C30H48O3 |
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| Beta-Amyrin |
559-70-6 |
4,4,6a,6b,8a,11,11,1
4b-octamethyl-1,2,3,
4a,5,6,7,8,9,10,12,1
2a,14,14a-
tetradec
ahydropicen-3-ol |
C30H50O |
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| Beta-Sitosterol |
5779-62-4 |
17-(5-ethyl-6-methyl
-heptan-2-yl)-10,13-
dimethyl-2,3,4,7,8,9
,11,12,14,
15,16,17
-dodecahydro-1H-cycl
openta[a]phenanthren
-3-ol |
C29H50O |
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| Plumericin |
77-16-7 |
Not Available |
C15H14O6 |
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| Isoplumericin |
31298-76-7 |
Not Available |
C15H14O6 |
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Pharmacology
| Medicinal Use |
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In nasopharyngeal cancer and leukemia (leaf extract); as an antifungal agent (flower). |
| Contraindication |
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All parts of the plant contain the iridoid lactone allamandin and may produce symptoms of vomiting or diarhea if ingested. |
| Reference |
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 Abdel-Kader MS. Wisse J. Evans R. van der Werff H. Kingston DG. Bioactive iridoids and a new lignan from Allamanda cathartica and Himatanthus fallax from the Suriname rainforest. J Nat Prod 1997 Dec;60(12):1294-7.
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