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Home » Raw Herbs » Leaves

Hypericum perforatum  L.

   

click to enlarge image

Botanical Name

:

Hypericum perforatum L.

English Name

:

St. John's Wort

Family

:

Clusiaceae

 

General Info

Description

It is an erect perennial herb that grows up to 32 inches tall. Commonly found in dry, gravelly soils, fields and sunny places in many parts of the world, including eastern North America and the Pacific coast. A woody branched root produces many round stems which put out runners from the base. The opposite, oblong to linear leaves are covered with transparent oil glands that look like holes. Flat topped cymes of yellow flowers, petals are dotted with black along the margins. The fruit is a three celled capsule containing small, dark brown seeds. The whole plant has turpentine-like odor.

Herb Effects

Sedative, antiinflammatory, antibacterial (against gram-positive types), antiviral, antioxidant, vasodilating, antidepressant, diuretic and cardiotonic, stimulates the immune system, inhibits tumors; inhibits the breakdown of CNS neurotransmitters.

Links

NCAM
Herb Information

Chemistry

Active Ingredients

Ascorbic acid, caryophyllene, choline, epicatechin, hyperforin, hyperin, hyperoside, isoquercitrin, limonene, lutein, mannitol, myrcene, palmitic acid, pinene, pyrogallol, quercetin, quercitrin, rutin.

Chemistry of Active Ingredients
Product Categories

Name

CAS#

IUPAC Name

Formula

Structure

Product Categories
Ascorbic acid Not Available 2-(1,2-dihydroxyethy
l)-4,5-dihydroxy-fur
an-3-one
C6H8O6 Click Here To Enlarge
Caryophyllene 87-44-5 4,11,11-trimethyl-8-
methylidene-bicyclo[
7.2.0]undec-4-ene
C15H24 Click Here To Enlarge
Choline 67-48-1 2-hydroxyethyl-trime
thyl-ammonium
C5H14NO+ Click Here To Enlarge
Epicatechin 490-46-0 2-(3,4-dihydroxyphen
yl)chroman-3,5,7-tri
ol
C15H14O6 Click Here To Enlarge
Hyperforin Not Available 4-hydroxy-8-methyl-3
,5,7-tris(3-methylbu
t-2-enyl)-8-(4-methy
lpent-3-en yl)-1-(2
-methylpropanoyl)bic
yclo[3.3.1]non-3-ene
-2,9-dione
C35H52O4 Click Here To Enlarge
Hyperin 482-36-0 2-(3,4-dihydroxyphen
yl)-4,5-dihydroxy-3-
[3,4,5-trihydroxy-6-
(hydroxyme thyl)oxa
n-2-yl]oxy-chromen-7
-one
C21H20O12 Click Here To Enlarge
Hyperoside 482-36-0 2-(3,4-dihydroxyphen
yl)-4,5-dihydroxy-3-
[3,4,5-trihydroxy-6-
(hydroxyme thyl)oxa
n-2-yl]oxy-chromen-7
-one
C21H20O12 Click Here To Enlarge
Isoquercitrin 21637-25-2 3-[5-(1,2-dihydroxye
thyl)-3,4-dihydroxy-
oxolan-2-yl]oxy-2-(3
,4-dihydro xyphenyl
)-4,5-dihydroxy-chro
men-7-one
C21H20O12 Click Here To Enlarge
Limonene 9003-73-0 1-methyl-4-prop-1-en
-2-yl-cyclohexene
C10H16 Click Here To Enlarge
Lutein 34445-91-5 4-[18-(4-hydroxy-2,6
,6-trimethyl-1-cyclo
hexenyl)-3,7,12,16-t
etramethyl -octadec
a-1,3,5,7,9,11,13,15
,17-nonaenyl]-3,5,5-
trimethyl-cyclohex-2
-e n-1-ol
C40H56O2 Click Here To Enlarge
Mannitol 85085-15-0 hexane-1,2,3,4,5,6-h
exaol
C6H14O6 Click Here To Enlarge
Myrcene 2153-31-3 7-methyl-3-methylide
ne-octa-1,6-diene
C10H16 Click Here To Enlarge
Palmitic acid 66321-94-6 hexadecanoic acid C16H32O2 Click Here To Enlarge
Pyrogallol Not Available benzene-1,2,3-triol C6H6O3 Click Here To Enlarge
Quercetin Not Available 2-(3,4-dihydroxyphen
yl)-3,4,5-trihydroxy
-chromen-7-one
C15H10O7 Click Here To Enlarge
Quercitrin 6151-25-3 2-(3,4-dihydroxyphen
yl)-4,5-dihydroxy-3-
(3,4,5-trihydroxy-6-
methyl-oxa n-2-yl)o
xy-chromen-7-one
C21H20O11 Click Here To Enlarge
Rutin Not Available 2-(3,4-dihydroxyphen
yl)-4,5-dihydroxy-3-
[3,4,5-trihydroxy-6-
[(3,4,5-tr ihydroxy
-6-methyl-tetrahydro
pyran-2-yl)oxymethyl
]tetrahydropyran-2-y
l] oxy-chromen-7-on
e trihydrate
C27H36O19 Click Here To Enlarge

Pharmacology

Medicinal Use

As an antidepressant, in mania, apathy, hypersomnia, and insomnia, anorexia, psychomotor retardation, depression feelings of worthlessness, anxiety disorders and aids in healing wounds and ulcers (for nervous disorders. the drug may take as long as a month before any effects are noticed). It is also used for menopausal changes triggering irritability and anxiety. In addition to neuralgic pain, it will ease fibrositis, sciatica and rheumatic pain.

Externally it is a healing and anti-inflammatory remedy. As a lotion it will speed the healing of wounds and bruises, varicose veins and mild burns. The oil is especially useful for the healing of sunburn. It has the calming properties, useful in treating bedwetting, insomnia, and other nervous conditions, as well as some form of melancholy. An oil extract of the herb can be taken for stomach ache, colic, intestinal problems, and as an expectorant for the congestion in the lungs. A tea made from the flowers is good for anemia, headache, insomnia, jaundice, chest congestion, and catarrh. A tea made from the herb has been used for uterine cramping and menstrual difficulties. The oil extract also make a good external application for burns, wounds, sores, bruises, and other skin problems.

Contraindication

Photosensitization may occur while taking this herb; pregnant or lactating women and people taking prescribed antidepressant medications should consult a physician before using this herb.

Reference

Grieve. M. A Modern Herbal. 1931 (www.botanical.com).


Secrets of St. John's Wort (Katzenstein).Bork PM. Bacher S. Schmitz ML. Kaspers U. Heinrich M. Hypericin as a non-antioxidant inhibitor of NF-kappa B. Planta Med1999 May;65(4):297-300.

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