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Botanical Name |
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Datura metel L. |
English
Name |
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Downy Datura or Dhatura |
Synonym(s) |
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Datura fastuosa (L.), Datura alba (Nees.) |
Family |
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Solanaceae |
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General Info
Description |
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It is a spreading herb sometimes remain shrubby. Leaves are ovate-lanceolate or broadly ovate, acute or acuminate, unequal at the base and often cordate, entire or dentate, sub-glabrous or with greyish tomentum, generally glandular in a long petiole of up to 10 cm in length. Flowers often double or triple. Calyx is inflated towards the middle, persistent and reflexes in fruit. Corolla is about twice as long as the calyx, white or tinged with green, pubescent outside and with the 10 toothed limb. Capsule is globose, tuberculate or muricate, borne on a short thick peduncle, which, unlike that of D. stramonium, is never erect but nodding. It dehisces irregularly exposing a mass of closely packed, light brown, flat seeds which nearly fill the interior. |
Herb Effects |
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The whole plant, but especially the leaves and seed, is anaesthetic, anodyne, antiasthmatic, antispasmodic, antitussive, bronchodilator, hallucinogenic, hypnotic and mydriatic; alleviates spasms and stimulates the cardiovascular system (fruit and plant); anthelmintic, anticancer, antiseptic, sedative and narcotic (plant); antiinflammatory and analgesic. |
Chemistry
Active Ingredients |
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Ferredoxin, datumetelin, daturilin, withametelin B, secowithametelin, a hexacyclic withanolide, physalinliconol, datumetixone, 12-deoxy withastramonolide and a P-methoxybenzoyl ester of tropine (leaf); daturadiol and daturaolone (fruit); scopolamine. |
Chemistry
of Active Ingredients |
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Name |
CAS# |
IUPAC Name |
Formula |
Structure |
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Daturadiol |
41498-79-7 |
4,4,6a,6b,8a,11,11,1 4b-octamethyl-1,2,3, 4a,5,6,7,8,9,10,12,1 2a,14,14a-
tetradec ahydropicene-3,5-dio l |
C30H50O2 |
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Daturaolone |
Not Available |
5-hydroxy-4,4,6a,6b, 8a,11,11,14b-octamet hyl-2,4a,5,6,7,8,9,1 0,12,12a,1
4,14a-do decahydro-1H-picen-3 -one |
C30H48O2 |
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Scopolamine |
97991-84-9 |
Not Available |
C17H21NO4 |
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Datumetelin |
Not Available |
(1S,5S,6R)-6-[(10R,1 3S)-10,13-dimethyl-1 -oxo-4,7,8,9,11,12,1 4,15,16,17
-decahyd rocyclopenta[a]phena nthren-17-yl]-2-(met hoxymethyl)-1-methyl -4
,8-dioxabicyclo[ 3.3.1]nonan-3-one |
C29H40O5 |
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Daturilin |
Not Available |
(1S,5S)-6-[(10R,13S) -10,13-dimethyl-1-ox o-4,7,8,9,11,12,14,1 5,16,17-de
cahydroc yclopenta[a]phenanth ren-17-yl]-1-methyl- 2-methylidene-4,8-di ox
abicyclo[3.3.1]n onan-3-one |
C28H36O4 |
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Scopolamine |
97991-84-9 |
Not Available |
C17H21NO4 |
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Pharmacology
Medicinal Use |
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Ophthalmia (seed decoction); asthma (flower); swolen areas and in rheumatism (leaf); to treat fever, worms, cracks in feet, filaria, chronic coryza, rabies, alopecia, skin diseases, boils, pain in breast and insanity (root, fruit and leaves); in the treatment of epilepsy, hysteria, insanity, heart diseases, fever with catarrh, diarrhoea, skin diseases and asthma (plant). |
Contraindication |
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Hot, dry, and flushed skin, hallucinations, pupil dilation, headache, delirium, rapid and weak pulse, convulsions, and coma. |
Reference |
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Chandel et al., Biodiversity in Medicinal and Aromatic Plants in India.
Uniyal et al., Medicinal Flora of Garhwal Himalayas.
The Himalaya Drug Company.
Cusido RM. Palazon J. Pinol MT. Bonfill M. Morales C. Datura metel: in vitro production. |
Dealers
Products
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