Andrographis paniculata (BURM.F.)WALLICH EX NEES |
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Botanical Name |
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Andrographis paniculata (BURM.F.)WALLICH EX NEES |
English
Name |
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The Creat |
Synonym(s) |
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Andrographis subspathulata C.B. Clarke, Justica paniculata Burm. f. |
Family |
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Acanthaceae |
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General Info
Description |
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It is an erect annual herb. Stem is dark green, quadrangular with longitudinal furrows and wings on the angles of the younger parts and slightly enlarged at the nodes. The leaves are glabrous, dark green, arranged opposite decussate, lanceolate and pinnate. The flowers are small, in lax spreading axillary and terminal racemes or panicles. The capsules are linear-oblong and acute at both ends. The seeds are numerous, sub-quadrate and yellowish brown in colour. |
Herb Effects |
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Astringent, anodyne, tonic, alexipharmic, tonic, febrifuge, stomachic, cholagogue, stimulant, aperient, antityphoid, antifungal, protects liver, antidiabetic and cholinergic (plant); lowers blood pressure (leaf); antibacterial (shoot). |
Chemistry
Active Ingredients |
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Andrographolide, neoandrographolide (plant); homoandrographolide, andrographosterol and andrographone (leaf). |
Chemistry
of Active Ingredients |
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Name |
CAS# |
IUPAC Name |
Formula |
Structure |
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Andrographolide |
5508-58-7 |
4-hydroxy-3-[2-[6-hy droxy-5-(hydroxymeth yl)-5,8a-dimethyl-2- methyliden
e-decali n-1-yl]ethylidene]ox olan-2-one |
C20H30O5 |
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Neoandrographolide |
Not Available |
3-[2-[(1S,4aR,5R,8aR )-5,8a-dimethyl-2-me thylidene-5-[[(2S,3R ,4S,5R,6R)
-3,4,5-t rihydroxy-6-(hydroxy methyl)oxan-2-yl]oxy methyl]decalin-1-yl] et
hyl]-5H-furan-2- one |
C26H40O8 |
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Pharmacology
Medicinal Use |
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Fever, stomach problems, diarrhea, dysentery and indigestion (plant decoction); auto-immune disorders, HIV/AIDS, heart disease, insect bites, cholera, diabetes, malaria, tuberculosis, rabies and snakebite. |
Contraindication |
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Although andrographis has been found to be safe in humans, animal studies suggest it may impair fertility. |
Reference |
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Chandel et al., Biodiversity in Medicinal and Aromatic Plants in India.
Bentley and Trimen, Medicinal Plants.
Johnson T. CRC Ethnobotany Desk Reference (www.herbweb.com/herbage). |
Dealers
Products
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