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Botanical Name |
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Allium sativum L. |
English
Name |
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Garlic, Poor-mans-treacle, Clove garlic |
Synonym(s) |
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Porrum sativum, Reichenb. Allium ophioscorodon, Don. |
Family |
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Liliaceae |
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General Info
Description |
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The leaves are long, narrow and flat like grass. The bulb is of a compound nature, consisting of numerous bulblets, known technically as 'cloves,' grouped together between the membraneous scales and enclosed within a whitish skin, which holds them as in a sac. The flowers are placed at the end of a stalk rising direct from the bulb and are whitish, grouped together in a globular head, or umbel, with an enclosing kind of leaf or spathae, and among them are small bulbils. |
Herb Effects |
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Anthelmintic, antiasthmatic, anticholesterolemic, antiseptic, cancer, cholagogue, diaphoretic, diuretic, expectorant, febrifuge, stimulant, stomachic, tonic, vasodilator, lowers serum blood cholesterol (while increasing the level of HDL), lowers blood fats, stimulates detoxifying enzymes (from the liver), antioxidant, antibiotic, antiseptic, antispasmodic, ascaricide and certain other parasites. |
Chemistry
Active Ingredients |
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Adenosine, ajoene, alanine, allicin, alliin, allyl propyl disulphide, alpha-phellandrene, alpha-tocopherol, arachidonic acid, arginine, aspartic acid, beta-phellandrene, biotin, caffeic acid, choline, citral, cycloallin, cystine, diallyl disulphide, diallyl-sulfide, diallyl-tetrasulfide, diallyl-trisulfide, ferulic acid, geraniol, glutamic acid, glutathione, glycine, histidine, isoleucine, methionine, nicotinic acid, p-coumaric acid, phenylalanine, quercetin, tryptophan, tyrosine (bulb); ascorbic acid, beta-carotene, niacin, riboflavin, thiamin (leaf, flower, bulb, shoot); beta-sitosterol, chlorogenic acid, kaempferol, oleanolic acid, oleic acid, p-hydroxy-benzoic acid, rutin, stigmasterol, succinic acid, taurine, (plant); ornithine (leaf) |
Chemistry
of Active Ingredients |
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Name |
CAS# |
IUPAC Name |
Formula |
Structure |
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Allyl propyl disulphide |
2179-59-1 |
3-propyldisulfanylpr op-1-ene |
C6H12S2 |
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Diallyl disulphide |
2179-57-9 |
3-prop-2-enyldisulfa nylprop-1-ene |
C6H10S2 |
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Alliin |
17795-27-6 |
2-amino-3-prop-2-eny lsulfinyl-propanoic acid |
C6H11NO3S |
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Riboflavin |
Not Available |
Not Available |
C17H21N4O9P |
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Niacin |
99148-57-9 |
pyridine-3-carboxyli c acid |
C6H5NO2 |
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Adenosine |
Not Available |
2-(6-aminopurin-9-yl )-5-(hydroxymethyl)o xolane-3,4-diol |
C10H13N5O4 |
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Ajoene |
92285-01-3 |
3-[(E)-3-prop-2-enyl sulfinylprop-1-enyl] disulfanylprop-1-ene |
C9H14OS3 |
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Alanine |
35597-43-4 |
2-[2-[2-amino-4-(hyd roxy-methyl-phosphor yl)-butanoyl]aminopr opanoylami
no]propa noic acid |
C11H22N3O6P |
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alpha-Phellandrene |
2243-33-6 |
2-methyl-5-propan-2- yl-cyclohexa-1,3-die ne |
C10H16 |
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Alpha-tocopherol |
364-50-1 |
2,5,7,8-tetramethyl- 2-(5,9,13-trimethylt etradecyl)chroman-6- ol |
C30H52O2 |
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Arachidonic acid |
7771-44-0 |
icosa-5,8,11,14-tetr aenoic acid |
C20H32O2 |
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Arginine |
7004-12-8 |
2-amino-5-guanidino- pentanoic acid |
C6H14N4O2 |
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Aspartic acid |
6899-03-2 |
2-aminobutanedioic acid |
C4H7NO4 |
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beta-Phellandrene |
555-10-2 |
3-methylidene-6-prop an-2-yl-cyclohexene |
C10H16 |
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Biotin |
58073-87-3 |
5-(7-oxo-3-thia-6,8- diazabicyclo[3.3.0]o ct-2-yl)pentanoic acid |
C10H16N2O3S |
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Caffeic acid |
Not Available |
3-(3,4-dihydroxyphen yl)prop-2-enoic acid |
C9H8O4 |
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Choline |
67-48-1 |
2-hydroxyethyl-trime thyl-ammonium |
C5H14NO+ |
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Citral |
96680-15-8 |
3,7-dimethylocta-2,6 -dienal |
C10H16O |
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Cycloallin |
455-41-4 |
(5S)-5-methyl-1-oxo- 1,4-thiazinane-2-car boxylic acid |
C6H11NO3S |
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Cystine |
24645-67-8 |
2-amino-3-(2-amino-2 -carboxy-ethyl)disul fanyl-propanoic acid |
C6H12N2O4S2 |
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Diallyl sulfide |
592-88-1 |
3-prop-2-enylsulfany lprop-1-ene |
C6H10S |
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Ferulic acid |
24276-84-4 |
3-(4-hydroxy-3-metho xy-phenyl)prop-2-eno ic acid |
C10H10O4 |
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Geraniol |
8007-13-4 |
3,7-dimethylocta-2,6 -dien-1-ol |
C10H18O |
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Glutamic acid |
Not Available |
2-aminopentanedioic acid |
C5H9NO4 |
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Glutathione |
27025-41-8 |
2-amino-5-[2-[2-(4-a mino-4-carboxy-butan oyl)amino-2-(carboxy methylcarb
amoyl)et hyl]disulfanyl-1-(ca rboxymethylcarbamoyl )ethyl]amino-5-oxo-p en
tanoic acid |
C20H32N6O12S2 |
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Glycine |
87867-94-5 |
2-aminoacetic acid |
C2H5NO2 |
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Histidine |
6027-02-7 |
2-amino-3-(3H-imidaz ol-4-yl)propanoic acid |
C6H9N3O2 |
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Isoleucine |
319-78-8 |
2-amino-3-methyl-pen tanoic acid |
C6H13NO2 |
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Methionine |
348-67-4 |
2-amino-4-methylsulf anyl-butanoic acid |
C5H11NO2S |
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Nicotinic acid |
99148-57-9 |
pyridine-3-carboxyli c acid |
C6H5NO2 |
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P-coumaric acid |
501-98-4 |
3-(4-hydroxyphenyl)p rop-2-enoic acid |
C9H8O3 |
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Phenylalanine |
3617-44-5 |
2-amino-3-phenyl-pro panoic acid |
C9H11NO2 |
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Quercetin |
Not Available |
2-(3,4-dihydroxyphen yl)-3,4,5-trihydroxy -chromen-7-one |
C15H10O7 |
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Tryptophan |
80206-30-0 |
2-amino-3-(1H-indol- 3-yl)propanoic acid |
C11H12N2O2 |
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Tyrosine |
556-02-5 |
2-amino-3-(4-hydroxy phenyl)-propanoic acid |
C9H11NO3 |
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Ascorbic Acid |
Not Available |
2-(1,2-dihydroxyethy l)-4,5-dihydroxy-fur an-3-one |
C6H8O6 |
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beta-Carotene |
Not Available |
3,7,12,16-tetramethy l-1,18-bis(2,6,6-tri methyl-1-cyclohexeny l)-octadec
a-1,3,5, 7,9,11,13,15,17-nona ene |
C40H56 |
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Thiamin |
59-43-8 |
2-[3-[(4-amino-2-met hyl-pyrimidin-5-yl)m ethyl]-4-methyl-1-th ia-3-azoni
acyclope nta-2,4-dien-5-yl]et hanol |
C12H17N4OS+ |
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Beta-sitosterol |
5779-62-4 |
17-(5-ethyl-6-methyl -heptan-2-yl)-10,13- dimethyl-2,3,4,7,8,9 ,11,12,14, |
C29H50O |
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Chlorogenic acid |
327-97-9 |
3-[3-(3,4-dihydroxyp henyl)prop-2-enoylox y]-1,4,5-trihydroxy- cyclohexan
e-1-carb oxylic acid |
C16H18O9 |
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Kaempferol |
80714-53-0 |
3-[3-[4,5-dihydroxy- 6-(hydroxymethyl)-3- [3,4,5-trihydroxy-6- (hydroxyme
thyl)oxa n-2-yl]oxy-oxan-2-yl ]oxy-4,5-dihydroxy-6 -(hydroxymethyl)oxan -2
-yl]oxy-4,5-dihy droxy-2-(4-hydroxyph enyl)-chromen-7-one |
C33H40O21 |
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Oleanolic acid |
508-02-1 |
10-hydroxy-2,2,6a,6b ,9,9,12a-heptamethyl -1,3,4,5,6,6a,7,8,8a ,10,11,12, 13,14b-tetradecahydr opicene-4a-carboxyli c acid |
C30H48O3 |
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Oleic acid |
8046-01-3 |
octadec-9-enoic acid |
C18H34O2 |
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p-Hydroxybenzoic acid |
99-96-7 |
4-hydroxybenzoic acid |
C7H6O3 |
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Rutin |
Not Available |
2-(3,4-dihydroxyphen yl)-4,5-dihydroxy-3- [3,4,5-trihydroxy-6- [(3,4,5-tr
ihydroxy -6-methyl-tetrahydro pyran-2-yl)oxymethyl ]tetrahydropyran-2-y l]
oxy-chromen-7-on e trihydrate |
C27H36O19 |
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Stigmasterol |
4736-55-4 |
17-(4-ethyl-1,5-dime thyl-hex-2-enyl)-10, 13-dimethyl-1,2,4,5, 6,7,8,9,10
,11,12,1 3,14,15,16,17-hexade cahydrocyclopenta[a] phenanthren-3-one |
C29H48O |
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Succinic acid |
6283-68-7 |
butanedioic acid |
C4H6O4 |
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Taurine |
91105-79-2 |
2-aminoethanesulfoni c acid |
C2H7NO3S |
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Ornithine |
1069-31-4 |
(2R)-2,5-diaminopent anoic acid |
C5H12N2O2 |
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Pharmacology
Medicinal Use |
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Arteriosclerosis, arthritis, asthma, athlete's foot; bladder, kidney and ear (including earache) ailments, boils, bronchitis, cancer, canker sores, common cold, corns, cough, dysmenorrhea, indigestion, fever, infections, inflammations, influenza and leukemia. |
Contraindication |
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Five commonly used herbs St John's wort, ginkgo biloba, valerian, garlic, and ginseng in Denmark were reported to produce potential drug interactions and adverse effects in clinical practice hence recommended for discontinuation before surgery. [Article in Danish] (Kistorp and Laursen, 2002).
Review of herb-drug interactions suggests Feverfew, garlic, Ginkgo, ginger, and ginseng may alter bleeding time and should not be used concomitantly with warfarin (Miller, 1998). |
Reference |
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Amagase H. Milner JA. Impact of various sources of garlic and their constituents on 7.12-dimethylbenz[a]anthracene binding to mammary cell DNA. Carcinogenesis 1993 Aug;14(8):1627-31.
Chandel et al., Biodiversity in Medicinal and Aromatic Plants in India.
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Dealers
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